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Oral Mucosal Immunity and Microbiome


Oral Mucosal Immunity and Microbiome


Advances in Experimental Medicine and Biology, Band 1197

von: Georgios N. Belibasakis, George Hajishengallis, Nagihan Bostanci, Michael A. Curtis

213,99 €

Verlag: Springer
Format: PDF
Veröffentl.: 15.11.2019
ISBN/EAN: 9783030285241
Sprache: englisch

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Beschreibungen

The first International Conference on Oral Mucosal Immunity and Microbiome (OMIM) aimed to highlight cutting-edge basic and translational research from an oral immunological and microbiological perspective. Oral diseases with a microbial etiology are the most prevalent chronic diseases of humans. Whilst not life-threatening, they can significantly compromise quality of life, are associated with increased risk for certain systemic diseases, and pose heavy financial burdens to national health systems. Hence, periodontal and peri-implant diseases, dental caries, root canal infections and mucosal infections are significant global public health problems.<div><div><br></div><div>In this book global experts summarize and discuss the latest progress made in oral mucosal immunity and the oral microbiome. Target audience is basic and/or translational researchers with expertise in host immunity and microbiome research, and interest in oral health and disease. This volume provides a much needed quantum leap in the field, by joining forces to address gaps at the oral mucosal immunity-microbiome cross-talk.&nbsp;</div></div>
1. Advances in oral mucosal immunity and the microbiome.- 2. Trained innate immunity and its implications for mucosal immunity and inflammation.- 3. Signaling systems in oral bacteria.- 4. Origin of Th17 cells in Type 2 Diabetes-Potentiated Periodontal Disease.- 5. Gingival epithelial cell recognition of lipopolysaccharide.- 6. The relationship of <i>Candida albicans</i> with the oral bacterial microbiome in health and disease.- 7. A potential role of Phospholipase 2 group IIA (PLA2-IIA) in <i>P. gingivalis</i>-induced oral dysbiosis.- 8. Helicobacter spp. in experimental models of colitis.- 9. T Helper 17 cells as pathogenic drivers of periodontitis.- 10. Candida-bacterial biofilms and host-microbe interactions in oral diseases.- 11. Comparative analysis of gene expression patterns for oral epithelium-related functions with aging.- 12. Neutrophil interaction with emerging oral pathogens: a novel view of the disease paradigm.- 13. Biologically-defined or biologically-informed traits are more heritable than clinically-defined ones: the case of oral and dental phenotypes.-&nbsp;
<div><div>Georgios N. Belibasakis</div><div>Karolinska Institute Department of Dental Medicine</div><div>Department of Dental Medicine</div><div>Huddinge</div><div>Stockholms Län</div><div>Sweden</div><div><br></div><div>Nagihan Bostanci</div><div>Karolinska Institute Department of Dental Medicine</div><div>Huddinge</div><div>Stockholms Län</div><div>Sweden</div><div><br></div><div>Michael A. Curtis</div><div>King's College London Dental Institute</div><div>London</div><div>United Kingdom</div><div><br></div><div>George Hajishengallis</div><div>Univ of Pennsylvania Penn Dental Med Microbio</div><div>Penn Dental Med Microbio</div><div>Philadelphia</div><div>Pennsylvania</div><div>USA</div><div><br></div><div><br></div><div><br></div><div><br></div><div><br></div><div><br></div><div><br></div><div><br></div></div>
The first International Conference on Oral Mucosal Immunity and Microbiome (OMIM) aimed to highlight cutting-edge basic and translational research from an oral immunological and microbiological perspective. Oral diseases with a microbial etiology are the most prevalent chronic diseases of humans. Whilst not life-threatening, they can significantly compromise quality of life, are associated with increased risk for certain systemic diseases, and pose heavy financial burdens to national health systems. Hence, periodontal and peri-implant diseases, dental caries, root canal infections and mucosal infections are significant global public health problems.<div><div><br></div><div>In this book global experts summarize and discuss the latest progress made in oral mucosal immunity and the oral microbiome. Target audience is basic and/or translational researchers with expertise in host immunity and microbiome research, and interest in oral health and disease. This volume provides a much needed quantum leap in the field, by joining forces to address gaps at the oral mucosal immunity-microbiome cross-talk.&nbsp;</div></div>
Highlights selections from the 1st International Conference on Oral Mucosal Immunity and Microbiome (OMIM), held in September 2018 Focuses on multi-omic technologies that are progressing the field of the oral microbiome Ideal reference for basic or translational researchers

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